Open-Access Virology Research

HPV Research

Data-driven analysis of Human Papillomavirus โ€” protein structures, genotype classification, epidemiology, and therapeutic targets. Open access, no paywalls.

Original Research

ORIGINAL RESEARCH 9 genotypes structurally analyzed
HPV E2 Protein: Structure, Function & Role in Viral Lifecycle
9 genotypes analyzed
Comprehensive analysis of the E2 protein across HPV genotypes showing that in high-risk strains, disruption of E2 upon integration leads to unchecked oncogene expression driving carcinogenesis.
ORIGINAL RESEARCH 12 therapeutic approaches analyzed
E2-Based Therapeutic Targets & Drug Development
E2 restoration strategies
Mapping therapeutic approaches that leverage E2 protein restoration to suppress HPV-driven oncogenesis.
ORIGINAL RESEARCH 14 genotypes compared
E2 Protein Genotype Comparison
Cross-strain structural analysis
Side-by-side comparison of E2 protein sequences and structural features across high-risk and low-risk HPV genotypes.
ORIGINAL RESEARCH 70% of high-risk HPV cancers show E2 disruption
E2 Integration & Cancer Progression
Viral integration mechanisms
How HPV E2 disruption during viral genome integration into host DNA drives progression from infection to cervical cancer.